Drug-resistant bacteria evolved on hedgehogs long before the use of antibiotics
Fungi on the animals produce natural antibiotics that may have promoted the evolution of resistance

Workers at wildlife rescue centers swabbed the noses, skin and feet of hundreds of European hedgehogs (Erinaceus europaeus shown), revealing that many of the critters harbored a type of MRSA superbug.
Hrald/Wikimedia Commons (CC BY-SA 3.0)